Description

1-Benzyl-4-Cyano-4-Hydroxypiperidine is a versatile piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique functional group arrangement, which enables its use in constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various pharmacologically active compounds, including potential central nervous system (CNS) agents and receptor modulators.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for constructing complex heterocyclic scaffolds and introducing cyano and hydroxyl functional groups.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D for exploring new synthetic pathways and reaction mechanisms.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemical intermediates, and other high-value-added products.
• Ligand and Catalyst Development: Its structure can be modified to create novel ligands for metal catalysis or organocatalysts.

Basic Information

Product Name	1-Benzyl-4-Cyano-4-Hydroxypiperidine
CAS No.	6094-60-6
Molecular Formula	C13H16N2O
Molecular Weight	216.28 g/mol
Synonyms	4-Hydroxy-1-benzyl-4-piperidinecarbonitrile; 4-Cyano-4-hydroxy-1-benzylpiperidine; 1-Benzyl-4-cyano-4-piperidinol; 4-Hydroxy-1-benzylpiperidine-4-carbonitrile; α-(4-Cyano-4-hydroxypiperidino)toluene; NSC 403697; 1-Benzyl-4-cyano-4-hydroxypiperidine; 4-Piperidinecarbonitrile, 4-hydroxy-1-(phenylmethyl)-
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4-Cyano-4-Hydroxypiperidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.