Description

iso-Butylmagnesium Chloride is a highly reactive organometallic compound, specifically a Grignard reagent, widely used as a powerful nucleophile and strong base in organic synthesis. Its value lies in its ability to efficiently introduce the iso-butyl group into target molecules, enabling the construction of complex carbon frameworks. This reagent is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials industries, where precise carbon-chain elongation and functional group transformations are required.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for introducing the iso-butyl moiety into active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Production: Used in the manufacture of pesticides, herbicides, and fungicides where specific branched-chain alkyl groups are needed for bioactivity.
• Fine Chemical & Specialty Chemical Manufacturing: Employed in the synthesis of flavors, fragrances, and performance chemicals requiring tailored alkylation.
• Polymer & Material Science: Serves as an initiator or modifying agent in the development of specialized polymers and advanced materials.
• Academic & Industrial R&D: A fundamental tool in exploratory chemistry for creating novel organic compounds and testing new synthetic methodologies.
• Catalyst Ligand Precursor: Can be used to prepare magnesium-based catalysts or as a precursor for other organometallic complexes.

Basic Information

Product Name	iso-Butylmagnesium Chloride
CAS No.	674-02-2
Molecular Formula	C4H9ClMg
Molecular Weight	116.87 g/mol
Synonyms	i-Butylmagnesium Chloride; (2-Methylpropyl)magnesium Chloride; Isobutylmagnesium Chloride; Magnesium, chloro(2-methylpropyl)-; Grignard Reagent i-BuMgCl; 2-Methylpropylmagnesium Chloride; Chloro(iso-butyl)magnesium
EINECS	211-611-6

Quality Control

Our iso-Butylmagnesium Chloride is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including titration for assay determination and gas chromatography (GC) for solvent and impurity profiling, to ensure high reactivity and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing purity, concentration, and relevant physical properties. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its pyrophoric and moisture-sensitive nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area, away from heat, ignition sources, and oxidizing agents. It is typically supplied and stored as a solution in specific organic solvents like diethyl ether or tetrahydrofuran (THF); consult the specific label or COA for the exact solvent and recommended storage temperature.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration (in specified solvent)	Typically 1.0M to 2.0M in THF or Ether
Assay (by Titration)	≥ 95.0% (of stated concentration)
Identification (IR/NMR)	Conforms to structure
Solvent (by GC)	As specified (e.g., THF, Diethyl Ether)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.