Description

Tetrafluorophenylphosphorane CAS NO 666-23-9 is a highly reactive organophosphorus compound characterized by a phosphorus center bonded to a pentafluorophenyl group. This compound is a valuable reagent in advanced chemical synthesis, serving as a versatile precursor for introducing fluorinated arylphosphine ligands and building blocks. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel materials, catalysts, and specialty chemicals, particularly within the pharmaceutical and agrochemical sectors.

Application

• Ligand Precursor in Catalysis: Serves as a key starting material for synthesizing sophisticated fluorinated phosphine ligands used in homogeneous catalysis, including cross-coupling and hydrogenation reactions.
• Pharmaceutical Intermediate: Employed in the research and development of active pharmaceutical ingredients (APIs), where the introduction of fluorinated phosphorous groups can modulate biological activity and metabolic stability.
• Agrochemical Synthesis: Used to create novel fluorinated organophosphorus compounds with potential applications as herbicides, insecticides, or plant growth regulators.
• Material Science Research: Acts as a building block for developing advanced polymers, flame retardants, or electronic materials that benefit from the unique properties of fluorine and phosphorus.
• Organic Synthesis Reagent: Functions as a phosphorylating or fluorinating agent in specialized organic transformations to create complex molecular architectures.

Basic Information

Item	Details
Product Name	Tetrafluorophenylphosphorane
CAS No.	666-23-9
Molecular Formula	C6F5P
Molecular Weight	198.03 g/mol
Synonyms	Pentafluorophenylphosphine; Pentafluorophenylphosphorane; (Pentafluorophenyl)phosphine; Phosphine, pentafluorophenyl-; Tetrafluorophenylphosphine; C6F5PH2; PFP
EINECS	Contact for details

Quality Control

Our Tetrafluorophenylphosphorane is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including NMR, GC, and elemental analysis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.