Description

Glycochenodeoxycholic Acid is a conjugated bile acid formed from the amide linkage of chenodeoxycholic acid with glycine. This compound is a critical biochemical intermediate and reference standard in life science research and pharmaceutical development. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity biochemicals for metabolic studies, drug discovery, and quality control processes.

Application

• Pharmaceutical Reference Standard: Used as a primary standard for the quality control and assay of bile acid-based pharmaceuticals and diagnostic kits.
• Metabolic Pathway Research: A key reagent in studying bile acid metabolism, liver function, and cholestatic liver diseases.
• Cell Signaling Studies: Investigated for its role as a signaling molecule and ligand for nuclear receptors like the farnesoid X receptor (FXR).
• Diagnostic Kit Manufacturing: Employed in the production of calibration standards and controls for clinical diagnostic assays measuring bile acid profiles.
• Biochemical Synthesis: Serves as a starting material or intermediate in the synthesis of more complex bile acid derivatives and conjugates.
• Academic & Industrial R&D: Utilized in basic research to understand digestive physiology and to develop novel therapeutic agents targeting metabolic disorders.

Basic Information

Product Name	Glycochenodeoxycholic Acid
CAS No.	640-79-9
Molecular Formula	C₂₆H₄₃NO₅
Molecular Weight	449.63 g/mol
Synonyms	Glycochenodeoxycholate; N-[(3α,5β,7α)-3,7-Dihydroxy-24-oxocholan-24-yl]glycine; Chenodeoxycholylglycine; GCDCA; Glycine chenodeoxycholic acid amide; 3α,7α-Dihydroxy-5β-cholan-24-oyl glycine
EINECS	211-382-5

Quality Control

Our Glycochenodeoxycholic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.