Description

3-Bromobenzoic Acid Bromide is a versatile and reactive aromatic acid halide derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to introduce both a bromine substituent and a highly reactive acid bromide functional group into target molecules, facilitating efficient carbon-carbon and carbon-heteroatom bond formation. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize complex intermediates, active pharmaceutical ingredients (APIs), and novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a brominated aromatic scaffold.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the bromine atom and acid bromide group enable specific bioactivity.
• Peptide Coupling Reagent: Acts as an efficient coupling agent in peptide synthesis for forming amide bonds between amino acids.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polymers, including high-performance resins and liquid crystals.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Derivatization: Used to prepare esters, amides, and other derivatives of 3-bromobenzoic acid for analytical standards or further synthetic steps.

Basic Information

Product Name	3-Bromobenzoic Acid Bromide
CAS No.	618-44-0
Molecular Formula	C7H4Br2O
Molecular Weight	263.92 g/mol
Synonyms	3-Bromobenzoyl Bromide; m-Bromobenzoyl Bromide; Benzoic acid, 3-bromo-, bromide; 3-Bromobenzoic acid bromide; 3-Bromobenzenecarbonyl bromide; m-Bromobenzoic acid bromide; α-Bromo-3-bromotoluene (obsolete); 3-Bromobenzoyl bromide
EINECS	210-558-9

Quality Control

Our 3-Bromobenzoic Acid Bromide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications, ensuring traceability and reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Isolate from incompatible materials such as strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.