Description

Cholesteryl Arachidonate is a high-purity ester formed from cholesterol and arachidonic acid, serving as a critical biochemical standard and research reagent. This compound is essential for studying lipid metabolism, membrane biophysics, and the role of cholesteryl esters in physiological and pathological processes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced life science sectors for analytical calibration, in-vitro studies, and as a precursor in specialized syntheses.

Application

• Biochemical Research Standard: Used as a certified reference material (CRM) for the quantification of cholesteryl esters in biological samples via LC-MS, GC, or HPLC.
• Lipidomics & Metabolic Studies: A key reagent in investigating atherosclerosis, lipid storage diseases, and cellular cholesterol trafficking pathways.
• Pharmaceutical Development: Employed as an intermediate or standard in the R&D of therapies targeting dyslipidemia and cardiovascular diseases.
• Cell Culture & Membrane Studies: Used to modify lipid composition in model membranes (liposomes) to study fluidity and signaling.
• Nutraceutical Analysis: Serves as an analytical standard for quality control in the dietary supplement industry for ω-6 and cholesterol-related products.

Basic Information

Product Name	Cholesteryl Arachidonate
CAS No.	604-34-2
Molecular Formula	C47H76O2
Molecular Weight	673.1 g/mol
Synonyms	Cholest-5-en-3β-ol 3-arachidonate; 5-Cholesten-3β-ol 3-arachidonate; Arachidonic acid cholesteryl ester; Cholesterol arachidonate; Cholesteryl 5,8,11,14-eicosatetraenoate; Cholesteryl ester (20:4); CE(20:4)
EINECS	Contact for details

Quality Control

Our Cholesteryl Arachidonate is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods (HPLC, GC, NMR). We support compliance with cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white waxy solid or oil
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95% (Area %)
Related Substances (HPLC)	Total impurities ≤5.0%
Solubility	Soluble in chloroform, DMSO, ethanol; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.