Description

Papaverine Hydrochloride is a pharmaceutical-grade alkaloid salt widely recognized for its potent vasodilatory and smooth muscle relaxant properties. This high-purity compound is critical for ensuring the efficacy and safety of various therapeutic formulations. It serves as an essential active pharmaceutical ingredient (API) and research chemical for manufacturers and laboratories in the pharmaceutical, biotechnology, and life sciences sectors.

Application

• Pharmaceutical API: Primary use as an active ingredient in injectable and oral formulations for treating vasospasm, cerebral ischemia, and certain types of impotence.
• Smooth Muscle Research: A key tool compound in pharmacological and physiological research for studying smooth muscle contraction and relaxation mechanisms.
• Vasodilator Formulations: Used in the development of medications aimed at improving blood flow in conditions like peripheral vascular disease.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical testing laboratories.
• Biochemical Synthesis: Employed as a chemical intermediate in the synthesis of more complex pharmaceutical compounds and derivatives.

Basic Information

Product Name	Papaverine Hydrochloride
CAS No.	61-25-6
Molecular Formula	C20H21NO4·HCl
Molecular Weight	375.85 g/mol
Synonyms	Papaverine HCl; 6,7-Dimethoxy-1-veratrylisoquinoline hydrochloride; Papaverinium chloride; Cerespan; Pavabid; (1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline) hydrochloride; Vasospan
EINECS	200-503-6

Quality Control

Our Papaverine Hydrochloride is manufactured and tested to meet stringent pharmacopeial standards, including USP and EP monographs where applicable. Every batch undergoes comprehensive analytical testing to ensure identity, potency, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) documenting results for assay, related substances, residual solvents, and microbiological attributes is provided to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.