Description

Ethanone, 1-[(3R,4R,5R)-2-Ethoxy-4,5-Dimethyl-2-Oxido-1,2-Oxaphospholan-3-Yl]-, Rel- (9Ci) is a high-purity, stereochemically defined organophosphorus compound. This material is a valuable chiral intermediate and building block for advanced synthesis in pharmaceutical and agrochemical research. It is specifically sought after by R&D chemists and process development scientists working on novel active ingredients, asymmetric catalysts, and complex molecule synthesis. The product is supplied under strict quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and neurological therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Catalyst Ligand Synthesis: Serves as a precursor for synthesizing sophisticated phosphorus-based ligands used in asymmetric catalysis (e.g., hydrogenation, cross-coupling).
• Chemical Biology Probes: Employed in the creation of molecular probes to study enzyme mechanisms and biological pathways involving phosphorylation.
• Material Science: Potential monomer or additive for specialty polymers where phosphorus incorporation can impart flame retardancy or other specific properties.
• Process Chemistry Development: Used for scaling up synthetic routes in pilot plants and optimizing manufacturing processes for commercial-scale production.

Basic Information

Product Name	Ethanone, 1-[(3R,4R,5R)-2-Ethoxy-4,5-Dimethyl-2-Oxido-1,2-Oxaphospholan-3-Yl]-, Rel- (9Ci)
CAS No.	599179-58-5
Molecular Formula	C9H17O5P
Molecular Weight	236.20 g/mol
Synonyms	rel-(3R,4R,5R)-3-Acetyl-2-ethoxy-4,5-dimethyl-1,2-oxaphospholane 2-oxide; 1-[(3R,4R,5R)-2-Ethoxy-4,5-dimethyl-2-oxido-1,2-oxaphospholan-3-yl]ethanone; (3R,4R,5R)-3-Acetyl-2-ethoxy-4,5-dimethyl-2-oxido-1,2-oxaphospholane; Chiral oxaphospholane derivative; Acetyl-substituted oxaphospholane oxide; Ethoxy-dimethyl-oxaphospholanyl ethanone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-[(3R,4R,5R)-2-Ethoxy-4,5-Dimethyl-2-Oxido-1,2-Oxaphospholan-3-Yl]-, Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to confirm identity, purity, and enantiomeric/excess. Certificates of Analysis (COA) are provided, detailing results from HPLC, NMR, and chiral analysis. We support development and commercial projects requiring highly consistent and traceable advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.