Description

tert-Butyl 1-(6-Chloropyrazin-2-Yl)Piperidin-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery and development. This compound serves as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily utilized by research institutions, contract research and manufacturing organizations (CROs/CMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop novel pharmacophores with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of specialized, non-commercially available compounds for client-specific research programs.
• Chemical Biology Probes: Can be utilized to create tool compounds for investigating biological pathways and target validation in early-stage drug discovery.

Basic Information

Product Name	tert-Butyl 1-(6-Chloropyrazin-2-Yl)Piperidin-4-Ylcarbamate
CAS No.	596817-48-0
Molecular Formula	C14H21ClN4O2
Molecular Weight	312.80 g/mol
Synonyms	4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-(6-chloro-2-pyrazinyl)piperidine; 1-Boc-4-amino-1-(6-chloropyrazin-2-yl)piperidine; tert-Butyl N-[1-(6-chloropyrazin-2-yl)piperidin-4-yl]carbamate; 1-(6-Chloro-pyrazin-2-yl)-piperidine-4-carboxylic acid tert-butylamide; BOC-Pip(6-Cl-Pyz)-NH2
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-(6-Chloropyrazin-2-Yl)Piperidin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.