Description

(+)-Costunolide CAS NO 591207-53-3 is a high-purity, bioactive sesquiterpene lactone, a key chiral building block and natural product of significant research interest. Its value lies in its potent and specific biological activities, which make it a critical reference standard and a promising lead compound for pharmaceutical and agrochemical development. This product is essential for researchers and manufacturers in pharmaceutical R&D, natural product chemistry, and life science research, particularly those investigating anti-inflammatory, anti-cancer, and neuroprotective agents.

Application

• Pharmaceutical Research & Development: Serves as a reference standard and a key intermediate for synthesizing novel therapeutic agents targeting inflammation, cancer, and neurological disorders.
• Natural Product Chemistry: Used as a pure, isolated compound for structure-activity relationship (SAR) studies, biosynthesis research, and as a marker for plant authentication.
• Life Science & Biochemical Research: Employed in in vitro and in vivo studies to elucidate biological pathways and mechanisms of action due to its well-defined bioactivity.
• Agrochemical Development: Investigated as a lead structure for developing new plant growth regulators or natural pesticide agents.
• Cosmeceutical Research: Explored for potential applications in skincare formulations for its reported anti-inflammatory and antioxidant properties.
• Academic & Institutional Laboratories: A fundamental reagent for graduate-level research and advanced studies in organic synthesis and medicinal chemistry.

Basic Information

Item	Detail
Product Name	(+)-Costunolide
CAS No.	591207-53-3
Molecular Formula	C15H20O2
Molecular Weight	232.32 g/mol
Synonyms	(+)-Costunolide; (3aR,6aR,9aS,9bR)-3a,4,5,8,9,9a-Hexahydro-6a,9b-dimethyl-3-methyleneazuleno[4,5-b]furan-2(3H)-one; (1R,7R,10S)-4,5,6,7,8,10-Hexahydro-1-methyl-7-(1-methylethenyl)-3H-3,10a-epoxyazulen-3-one; Costunolide, (+)-; Dehydrocostus lactone (enantiomer); Saussurea lactone; Contact for EINECS details.

Quality Control

Our (+)-Costunolide is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (IR, NMR). A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.