Description

Imidazo[1,5-A]Pyrazine-6-Carboxamide, n-(1S,2R,4R)-7-Azabicyclo[2.2.1]Hept- is a high-purity, advanced pharmaceutical intermediate characterized by its complex, stereochemically defined bicyclic structure. This compound is of critical importance for the research and development of novel therapeutic agents, particularly in the fields of neurology and metabolic disease. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules and investigational new drugs (INDs).
• Neurological Drug Research: Serves as a core scaffold for developing compounds targeting neurological receptors and pathways.
• Metabolic Disease Research: Used in the development of potential treatments for metabolic disorders due to its specific molecular architecture.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	Imidazo[1,5-A]Pyrazine-6-Carboxamide, n-(1S,2R,4R)-7-Azabicyclo[2.2.1]Hept-
CAS No.	588726-80-1
Molecular Formula	C12H15N5O
Molecular Weight	245.28 g/mol
Synonyms	N-[(1S,2R,4R)-7-Azabicyclo[2.2.1]hept-2-yl]imidazo[1,5-a]pyrazine-6-carboxamide; (1S,2R,4R)-N-(7-Azabicyclo[2.2.1]hept-2-yl)imidazo[1,5-a]pyrazine-6-carboxamide; 7-Azabicyclo[2.2.1]heptane-2-carboxamide, N-imidazo[1,5-a]pyrazin-6-yl-, (1S,2R,4R)-; Imidazo[1,5-a]pyrazine-6-carboxylic acid, 2-[(1S,2R,4R)-7-azabicyclo[2.2.1]hept-2-yl]amide
EINECS	Contact for details

Quality Control

Our Imidazo[1,5-A]Pyrazine-6-Carboxamide intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, NMR, and mass spectrometry for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment. Production can adhere to cGMP guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.