Description

Imidazo[1,2-A]Pyrazine-6-Carboxamide, n-(1S,2R,4R)-7-Azabicyclo[2.2.1]Hept- CAS NO 588726-79-8 is a high-purity, advanced pharmaceutical intermediate characterized by its complex, chiral bicyclic structure. This compound is of critical importance for the research and development of novel therapeutic agents, particularly in the fields of oncology and virology. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted, small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of investigational new drugs (INDs) and new chemical entities (NCEs).
• Oncology Research: Used in the development of kinase inhibitors and other targeted cancer therapies.
• Antiviral Drug Development: Serves as a core scaffold for compounds targeting viral replication enzymes.
• Chemical Biology & Proteomics: Employed as a molecular probe to study enzyme function and protein-ligand interactions.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and cGMP manufacturing of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRAM): Sourced by CDMOs for custom synthesis projects requiring high stereochemical purity.

Basic Information

Product Name	Imidazo[1,2-A]Pyrazine-6-Carboxamide, n-(1S,2R,4R)-7-Azabicyclo[2.2.1]Hept- CAS NO 588726-79-8
CAS No.	588726-79-8
Molecular Formula	C12H15N5O
Molecular Weight	245.28 g/mol
Synonyms	N-[(1S,2R,4R)-7-Azabicyclo[2.2.1]hept-2-yl]imidazo[1,2-a]pyrazine-6-carboxamide; (1S,2R,4R)-N-(7-Azabicyclo[2.2.1]hept-2-yl)imidazo[1,2-a]pyrazine-6-carboxamide; Imidazo[1,2-a]pyrazine-6-carboxamide, N-[(1S,2R,4R)-7-azabicyclo[2.2.1]hept-2-yl]-; 588726-79-8; 7-Azabicyclo[2.2.1]heptane-2-carboxamide, N-(imidazo[1,2-a]pyrazin-6-yl)-, (1S,2R,4R)-
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up work. Identity, purity, and chiral integrity are verified using advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with every shipment. We support development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.