Description

Imidazo[1,5-A]Pyrazine-6-Carboxamide, n-2-Azabicyclo[2.2.1]Hept-5-Yl- (9Ci) is a sophisticated heterocyclic organic compound featuring a fused imidazopyrazine core linked to a bridged azabicyclic system. This complex molecular architecture makes it a highly valuable pharmaceutical intermediate and key building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Protease Inhibitor Development: The structural motif is relevant in the design and synthesis of protease inhibitors for antiviral and anticancer applications.
• Kinase Inhibitor Synthesis: Acts as a core building block for the development of novel kinase inhibitors, a major class of targeted cancer therapies.
• Chemical Biology Probes: Employed in the creation of specialized chemical probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	Imidazo[1,5-A]Pyrazine-6-Carboxamide, n-2-Azabicyclo[2.2.1]Hept-5-Yl- (9Ci)
CAS No.	588725-52-4
Molecular Formula	C12H15N5O
Molecular Weight	245.28 g/mol
Synonyms	N-(2-Azabicyclo[2.2.1]hept-5-yl)imidazo[1,5-a]pyrazine-6-carboxamide; 2-Azabicyclo[2.2.1]hept-5-amine, N-(imidazo[1,5-a]pyrazin-6-ylcarbonyl)-; Imidazo[1,5-a]pyrazine-6-carboxamide, N-(2-azabicyclo[2.2.1]hept-5-yl)-; 588725-52-4; UNII-9H8L8L8U4W; 9H8L8L8U4W; AKOS025310999; AS-57811
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical characterization using techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. We support both research and development-scale projects with appropriate documentation. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom purity grades or analytical packages can be discussed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider holding under an inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.