Description

Pyrrolo[1,2-a]pyrazine-3-carboxylic acid (9CI) is a heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its fused bicyclic structure makes it a valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought by research and development chemists, process development scientists, and manufacturers engaged in the production of active pharmaceutical ingredients (APIs), fine chemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the synthesis of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex organic molecules, dyes, and functional materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical spaces.
• Ligand and Catalyst Development: The carboxylic acid and nitrogen-containing heterocycle provide sites for coordination, useful in designing novel catalysts or metal-organic frameworks (MOFs).

Basic Information

Product Name	Pyrrolo[1,2-a]pyrazine-3-carboxylic acid (9CI)
CAS No.	588720-53-0
Molecular Formula	C7H6N2O2
Molecular Weight	150.14 g/mol
Synonyms	1H-Pyrrolo[1,2-a]pyrazine-3-carboxylic acid; Pyrrolo[1,2-a]pyrazine-3-carboxylic acid; 3-Pyrrolo[1,2-a]pyrazinecarboxylic acid; 588720-53-0; Pyrrolopyrazine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of Pyrrolo[1,2-a]pyrazine-3-carboxylic acid adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity (by IR, NMR), and related substance profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.