Description

Pyrrolo[1,2-C]Pyrimidine-3-Carboxamide, n-(1R,3R,4S)-1-Azabicyclo[2.2.1]Hept- is a high-purity, advanced pharmaceutical intermediate characterized by its complex, rigid bicyclic structure. This compound is of significant commercial importance for the research and development of novel therapeutic agents, particularly in the field of central nervous system (CNS) and neurological disorders. It is primarily sought by pharmaceutical R&D laboratories, biotechnology firms, and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Preclinical Development: Serves as a critical intermediate for producing compounds for pharmacological and toxicological evaluation.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying enzyme function and receptor interactions.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of complex, high-value molecules.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and drug discovery projects.

Basic Information

Product Name	Pyrrolo[1,2-C]Pyrimidine-3-Carboxamide, n-(1R,3R,4S)-1-Azabicyclo[2.2.1]Hept-
CAS No.	588720-21-2
Molecular Formula	C12H14N4O
Molecular Weight	230.27 g/mol
Synonyms	N-[(1R,3R,4S)-1-Azabicyclo[2.2.1]hept-3-yl]pyrrolo[1,2-c]pyrimidine-3-carboxamide; (1R,3R,4S)-N-(1-Azabicyclo[2.2.1]hept-3-yl)pyrrolo[1,2-c]pyrimidine-3-carboxamide; Pyrrolo[1,2-c]pyrimidine-3-carboxamide, N-[(1R,3R,4S)-1-azabicyclo[2.2.1]hept-3-yl]-; 588720-21-2; Bicyclic pyrrolopyrimidine carboxamide; Nor-tropane pyrrolopyrimidine derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer this intermediate in high-purity grades suitable for pharmaceutical research and development. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles. Production can be aligned with cGMP (current Good Manufacturing Practice) standards for advanced development phases upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term stability is required. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.