Description

Piperazine, 1-[(3-Chloro-4-Fluorobenzo[B]Thien-2-Yl)Carbonyl]-4-(3-Chlorophenyl)- (9Ci) is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly in the creation of novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories specializing in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel, high-value active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug discovery programs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Preclinical Development: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in API production.

Basic Information

Product Name	Piperazine, 1-[(3-Chloro-4-Fluorobenzo[B]Thien-2-Yl)Carbonyl]-4-(3-Chlorophenyl)- (9Ci)
CAS No.	588675-51-8
Molecular Formula	C20H15Cl2FN2OS
Molecular Weight	421.31 g/mol
Synonyms	1-[(3-Chloro-4-fluorobenzo[b]thiophen-2-yl)carbonyl]-4-(3-chlorophenyl)piperazine; 4-(3-Chlorophenyl)-1-[(3-chloro-4-fluorobenzo[b]thien-2-yl)carbonyl]piperazine; 1-(3-Chloro-4-fluorobenzo[b]thien-2-carbonyl)-4-(3-chlorophenyl)piperazine; 588675-51-8; UNII-3C6W6W8Q6H; 3C6W6W8Q6H; AOB67779; SCHEMBL21806279; BDBM50388855; AKOS025310923; Z57128351
EINECS	Contact for details

Quality Control

Every batch of this pharmaceutical intermediate is produced and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and compliance with cGMP guidelines where applicable. Our quality commitment supports your regulatory filings and ensures batch-to-batch consistency for critical R&D and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.