Description

Piperazine, 1-[(3-Chloro-4-Fluorobenzo[B]Thien-2-Yl)Carbonyl]-4-(4-Fluorophenyl)- (9Ci) is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly in the creation of novel therapeutic agents. It is primarily needed by pharmaceutical manufacturers, contract research organizations (CROs), and fine chemical suppliers engaged in the development of new drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in multi-step synthesis routes for target APIs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Biochemical Research: Potential use as a tool compound for investigating biological pathways and protein interactions.
• Fine Chemical Synthesis: Employed in the production of other specialized, high-value fluorinated and heterocyclic compounds.

Basic Information

Product Name	Piperazine, 1-[(3-Chloro-4-Fluorobenzo[B]Thien-2-Yl)Carbonyl]-4-(4-Fluorophenyl)- (9Ci)
CAS No.	588675-50-7
Molecular Formula	C20H15ClF2N2OS
Molecular Weight	404.86 g/mol
Synonyms	1-[(3-Chloro-4-fluorobenzo[b]thiophen-2-yl)carbonyl]-4-(4-fluorophenyl)piperazine; 4-(4-Fluorophenyl)-1-[(3-chloro-4-fluorobenzo[b]thien-2-yl)carbonyl]piperazine; 1-(3-Chloro-4-fluorobenzo[b]thiophene-2-carbonyl)-4-(4-fluorophenyl)piperazine; 588675-50-7; UNII-7K8Q6Q5F2F; 7K8Q6Q5F2F; SCHEMBL21804227; AKOS025310647; BDBM50388857.
EINECS	Contact for details

Quality Control

Our Piperazine, 1-[(3-Chloro-4-Fluorobenzo[B]Thien-2-Yl)Carbonyl]-4-(4-Fluorophenyl)- (9Ci) is manufactured under strict quality systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request. Our quality commitment aligns with cGMP principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Handle and store in accordance with good laboratory and manufacturing practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.