Description

Piperazine, 1-[(3-Chloro-4-Fluorobenzo[B]Thien-2-Yl)Carbonyl]-4-Ethyl- (9Ci) is a specialized heterocyclic compound featuring a piperazine core functionalized with a substituted benzothiophene carbonyl group. This molecular architecture makes it a valuable advanced pharmaceutical intermediate (API intermediate) for the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, particularly for targeting central nervous system and oncological pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry research.
• Drug Discovery & Development: Used in high-throughput screening and lead optimization for creating new drug candidates with potential biological activity.
• Chemical Synthesis Research: Acts as a key reagent for constructing complex heterocyclic frameworks in academic and industrial R&D laboratories.
• Preclinical Studies: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Custom Synthesis: Available for contract manufacturing organizations (CMOs) requiring specific, high-purity intermediates for client projects.
• Life Science Reagents: Supplied to companies producing biochemicals and reagents for scientific research.

Basic Information

Product Name	Piperazine, 1-[(3-Chloro-4-Fluorobenzo[B]Thien-2-Yl)Carbonyl]-4-Ethyl- (9Ci)
CAS No.	588675-48-3
Molecular Formula	C16H16ClFN2OS
Molecular Weight	338.83 g/mol
Synonyms	1-[(3-Chloro-4-fluorobenzo[b]thien-2-yl)carbonyl]-4-ethylpiperazine; 4-Ethyl-1-[(3-chloro-4-fluorobenzo[b]thiophene-2-carbonyl)]piperazine; 1-(3-Chloro-4-fluorobenzo[b]thiophene-2-carbonyl)-4-ethylpiperazine; N-(3-Chloro-4-fluorobenzo[b]thien-2-yl)-4-ethylpiperazine-1-carboxamide; 588675-48-3; Ethylpiperazine derivative; Benzo[b]thiophene piperazine carboxamide
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay purity and impurity profiles. We support development and commercial projects with custom purity grades and specifications tailored to your synthetic requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0% (Area Percent)
Purity (HPLC)	≥ 98.0% (Total area)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.