Description

Pyrazolo[3,4-B]Azepine, 3-(1-Ethyl-2-Piperidinyl)-1,4,5,6,7,8-Hexahydro- (9Ci) is a complex, nitrogen-rich heterocyclic compound belonging to the fused pyrazoloazepine class, serving as a sophisticated pharmacological building block and key synthetic intermediate. Its unique molecular architecture, featuring a bridged piperidine moiety, makes it highly valuable for constructing novel chemical entities with targeted biological activity. This advanced intermediate is primarily sought by pharmaceutical R&D teams and contract research organizations (CROs) engaged in drug discovery programs, particularly for central nervous system (CNS) and receptor-targeted therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), especially for neurological and psychiatric drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries to identify new lead compounds.
• Ligand Synthesis: Employed in the development of selective receptor ligands and enzyme inhibitors due to its ability to mimic specific pharmacophores.
• Chemical Biology Probes: Serves as a starting material for creating labeled compounds or probes used to study biological pathways and target engagement.
• Process Chemistry Development: Utilized in route scouting and optimization for the scalable production of complex drug molecules under Good Manufacturing Practice (GMP) guidelines.
• Academic Research: A valuable compound for universities and research institutes studying heterocyclic chemistry, synthetic methodology, and new therapeutic modalities.

Basic Information

Item	Information
Product Name	Pyrazolo[3,4-B]Azepine, 3-(1-Ethyl-2-Piperidinyl)-1,4,5,6,7,8-Hexahydro- (9Ci)
CAS No.	585520-40-7
Molecular Formula	C14H23N3
Molecular Weight	233.36 g/mol
Synonyms	3-(1-Ethyl-2-piperidinyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-b]azepine; 1,4,5,6,7,8-Hexahydro-3-(1-ethyl-2-piperidinyl)pyrazolo[3,4-b]azepine; 3-(1-Ethylpiperidin-2-yl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-b]azepine; Pyrazolo[3,4-b]azepine, 3-(1-ethyl-2-piperidinyl)-1,4,5,6,7,8-hexahydro-; SCHEMBL23545427; AKOS040759232; ZINC000004139756
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting critical quality attributes. For development and commercial projects, we can align our quality standards with GMP guidelines and customer-specific protocols upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.