Description

(3R,8As)-Rel-Hexahydro-3-(Hydroxymethyl)-8A-Methyl-5-Oxo-7H-Oxazolo[3,2-A]Pyrazine-7-Carboxylic Acid Phenylmethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex oxazolopyrazine core structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and process chemistry optimization.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Process Research & Development (R&D): Used in route scouting and optimization studies for the commercial-scale production of target APIs.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and validation in quality control laboratories.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry, reaction mechanisms, and structure-activity relationships (SAR).
• Custom Synthesis: Acts as a starting material for the custom synthesis of specialized derivatives and analogs for client-specific research programs.

Basic Information

Product Name	(3R,8As)-Rel-Hexahydro-3-(Hydroxymethyl)-8A-Methyl-5-Oxo-7H-Oxazolo[3,2-A]Pyrazine-7-Carboxylic Acid Phenylmethyl Ester
CAS No.	579467-28-0
Molecular Formula	C16H20N2O5
Molecular Weight	320.34 g/mol
Synonyms	Benzyl (3R,8aR)-hexahydro-3-(hydroxymethyl)-8a-methyl-5-oxo-7H-oxazolo[3,2-a]pyrazine-7-carboxylate; (3R,8aR)-Hexahydro-3-(hydroxymethyl)-8a-methyl-5-oxo-7H-oxazolo[3,2-a]pyrazine-7-carboxylic acid phenylmethyl ester; Oxazolopyrazine derivative 579467-28-0; 7H-Oxazolo[3,2-a]pyrazine-7-carboxylic acid, hexahydro-3-(hydroxymethyl)-8a-methyl-5-oxo-, phenylmethyl ester, (3R,8aR)-rel-; Benzyl (3R,8aR)-rel-hexahydro-3-(hydroxymethyl)-8a-methyl-5-oxo-7H-oxazolo[3,2-a]pyrazine-7-carboxylate
EINECS	Contact for details

Quality Control

Our (3R,8As)-Rel-Hexahydro-3-(Hydroxymethyl)-8A-Methyl-5-Oxo-7H-Oxazolo[3,2-A]Pyrazine-7-Carboxylic Acid Phenylmethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.