Description

5H-Oxazolo[3,2-A]Pyrazin-5-One,Hexahydro-3,8A-Dimethyl-,(3R,8As)-Rel-(9Ci) is a high-purity, stereochemically defined heterocyclic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its complex fused oxazolopyrazine structure makes it a valuable building block for the development of novel pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of new chemical entities, particularly for high-value applications in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Medicinal Chemistry Research: Used as a core scaffold or a sophisticated precursor for constructing compound libraries in high-throughput screening (HTS) campaigns to identify new bioactive leads.
• Process Chemistry Development: Employed in route scouting and optimization studies for the scalable production of complex target molecules during preclinical and clinical development phases.
• Academic Research: Serves as a substrate for studying novel organic reactions, asymmetric synthesis methodologies, and the properties of fused heterocyclic systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations that require high-quality, well-characterized building blocks for client-sponsored discovery and development projects.

Basic Information

Product Name	5H-Oxazolo[3,2-A]Pyrazin-5-One,Hexahydro-3,8A-Dimethyl-,(3R,8As)-Rel-(9Ci)
CAS No.	579467-22-4
Molecular Formula	C8H12N2O2
Molecular Weight	168.19 g/mol
Synonyms	rel-(3R,8aS)-Hexahydro-3,8a-dimethyl-5H-oxazolo[3,2-a]pyrazin-5-one; (3R,8aS)-rel-Hexahydro-3,8a-dimethyl-5H-[1,3]oxazolo[3,2-a]pyrazin-5-one; 5H-Oxazolo[3,2-a]pyrazin-5-one, hexahydro-3,8a-dimethyl-, (3R,8aS)-rel-; SCHEMBL21821027; AOB31117; AKOS040751090; ZINC000257400509
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality management systems to ensure identity, purity, and stereochemical integrity. Our standard quality commitment includes comprehensive analytical characterization using techniques such as HPLC, GC, NMR, and chiral analysis to confirm compliance with client specifications. A detailed Certificate of Analysis (COA) documenting all critical quality attributes is provided with each shipment. For projects requiring specific regulatory support, we can discuss compliance with ICH Q7 guidelines and other relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider holding under an inert atmosphere to maintain optimal stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.