Description

Resolvin D5 CAS NO 578008-43-2 is a specialized pro-resolving lipid mediator (SPM) belonging to the resolvin family, derived from the ω-3 fatty acid docosahexaenoic acid (DHA). This compound is of significant interest for its potent and specific biological activity in actively resolving inflammation and promoting tissue homeostasis. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and advanced life science sectors for drug discovery, mechanism-of-action studies, and the development of novel therapeutic agents targeting chronic inflammatory diseases.

Application

• Pharmaceutical Research & Drug Discovery: As a reference standard and active investigational compound for developing new anti-inflammatory and pro-resolving therapies.
• Biochemical Research: For in vitro and in vivo studies to elucidate signaling pathways involved in the resolution phase of inflammation.
• Cell Biology & Immunology: Used to study macrophage function, neutrophil clearance, and other immune cell activities in model systems.
• Bioactive Compound Synthesis: Serves as a key intermediate or target molecule for synthetic and medicinal chemists.
• Diagnostic Development: Potential use in developing assays to monitor resolvin pathways in clinical or preclinical samples.
• Nutraceutical & Cosmetic Research: Investigation into topical or systemic applications for managing skin inflammation or promoting healing.

Basic Information

Product Name	Resolvin D5
CAS No.	578008-43-2
Molecular Formula	C22H32O5
Molecular Weight	376.49 g/mol
Synonyms	RvD5; (7S,17S)-Dihydroxy-4Z,8E,10Z,13Z,15E,19Z-docosahexaenoic acid; Resolvin D5; 7S,17S-diHDHA; Specialized Pro-resolving Mediator D5; Inflammation Resolving Mediator D5
EINECS	Contact for details

Quality Control

Our Resolvin D5 is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity, essential for reliable research outcomes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). This product is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers should be sealed immediately after use and allowed to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.