Description

1-Piperazinecarboxylic Acid, 2,6-Dimethyl-, 1,1-Dimethylethyl Ester, (2R,6R)- is a high-purity, stereochemically defined chiral piperazine derivative. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in sophisticated organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs), particularly in areas requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug molecules, especially those targeting neurological and cardiovascular disorders.
• API Synthesis: Used in the research, development, and commercial production of Active Pharmaceutical Ingredients (APIs) where the (2R,6R)- stereochemistry is pharmacologically essential.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in asymmetric catalytic reactions to induce stereoselectivity.
• Medicinal Chemistry Research: A valuable scaffold for constructing compound libraries in drug discovery and lead optimization programs.
• Peptidomimetics: Used in the design and synthesis of peptide analogs and peptidomimetic compounds with enhanced metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts.

Basic Information

Item	Detail
Product Name	1-Piperazinecarboxylic Acid, 2,6-Dimethyl-, 1,1-Dimethylethyl Ester, (2R,6R)-
CAS No.	574007-62-8
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	(2R,6R)-2,6-Dimethylpiperazine-1-carboxylic acid tert-butyl ester; tert-Butyl (2R,6R)-2,6-dimethylpiperazine-1-carboxylate; (R,R)-2,6-Dimethylpiperazine-1-carboxylic acid tert-butyl ester; (2R,6R)-Boc-2,6-dimethylpiperazine; Boc-(R,R)-2,6-dimethylpiperazine; (R,R)-Boc-2,6-DMP; (2R,6R)-1-Boc-2,6-dimethylpiperazine; (R,R)-1-N-Boc-2,6-dimethylpiperazine
EINECS	Contact for details

Quality Control

Our (2R,6R)-2,6-Dimethylpiperazine-1-carboxylic acid tert-butyl ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for chiral purity and chemical assay, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications for identity, purity, and impurities are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (2R,6R)-isomer
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.