Description

1-Boc-4-(2-Amino-4-Pyridinyl)-Piperazine is a high-purity, protected piperazine derivative of significant importance in modern pharmaceutical research and development. This compound serves as a critical versatile building block for the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology sectors for creating novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Scaffold: Used to construct diverse chemical libraries for high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• API Synthesis: Integral in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), leveraging its protected amine functionality.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Agrochemical Research: Serves as a building block for developing novel crop protection agents and pesticides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-Boc-4-(2-Amino-4-Pyridinyl)-Piperazine
CAS No.	571189-23-6
Molecular Formula	C14H22N4O2
Molecular Weight	278.35 g/mol
Synonyms	1-Boc-4-(2-Amino-4-pyridyl)piperazine; tert-Butyl 4-(2-amino-4-pyridinyl)-1-piperazinecarboxylate; 4-(2-Amino-4-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(2-amino-4-pyridinyl)piperazine; N-Boc-4-(2-amino-4-pyridinyl)piperazine; 571189-23-6; 1-Piperazinecarboxylic acid, 4-(2-amino-4-pyridinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(2-Amino-4-Pyridinyl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and cGMP (current Good Manufacturing Practice) starting materials where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.