Description

3-Pyrrolidinol, 4-(4-Chlorophenoxy)-, trans- is a specialized chiral pyrrolidine derivative, a high-value intermediate in modern synthetic chemistry. Its molecular architecture, featuring a trans-substituted pyrrolidine ring and a 4-chlorophenoxy moiety, makes it a critical building block for the development of advanced pharmaceuticals and agrochemicals. This compound is primarily sought by research and development chemists, process chemists, and manufacturers in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the chlorophenoxy group.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis.
• Chemical Biology Probe Development: Employed in medicinal chemistry to build molecular probes for studying biological targets and pathways.
• Custom Synthesis and Contract Manufacturing: A critical component for custom synthesis houses serving the life sciences industry.
• Academic and Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	3-Pyrrolidinol, 4-(4-Chlorophenoxy)-, trans-
CAS No.	565453-25-0
Molecular Formula	C10H12ClNO2
Molecular Weight	213.66 g/mol
Synonyms	trans-4-(4-Chlorophenoxy)-3-pyrrolidinol; (3R,4R)-4-(4-Chlorophenoxy)-3-pyrrolidinol; (3S,4S)-4-(4-Chlorophenoxy)-3-pyrrolidinol; 4-(4-Chlorophenoxy)-3-pyrrolidinol (trans-); 1-Azabicyclo[3.2.0]heptan-3-ol, 6-(4-chlorophenoxy)-, (1R,5R,6S)-rel-; 565453-25-0; 4-(p-Chlorophenoxy)-3-pyrrolidinol
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidinol, 4-(4-Chlorophenoxy)-, trans- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.