Description

Piperidine, 1-[(2R)-Oxiranylmethyl]- (9Ci) is a specialized chiral piperidine derivative featuring an oxiranylmethyl substituent. This compound is a high-value intermediate of significant interest in the synthesis of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily sought after by research institutions and manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and fine chemicals. Its defined stereochemistry and reactive epoxide moiety make it a critical building block for constructing sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, especially for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in custom synthesis and scale-up projects for high-purity specialty chemicals.
• Academic and R&D Laboratories: Utilized in medicinal chemistry programs and methodological studies for ring-opening and functionalization reactions.

Basic Information

Product Name	Piperidine, 1-[(2R)-Oxiranylmethyl]- (9Ci)
CAS No.	561023-59-4
Molecular Formula	C8H15NO
Molecular Weight	141.21 g/mol
Synonyms	1-[(2R)-Oxiranylmethyl]piperidine; (R)-1-(Oxiran-2-ylmethyl)piperidine; (R)-Glycidyl piperidine; (2R)-1-(Piperidin-1-ylmethyl)oxirane; 1-[(R)-Oxiranylmethyl]piperidine; (R)-Epoxypropyl piperidine; Piperidine, 1-[(R)-glycidyl]-; 561023-59-4
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral intermediates. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, ensuring batch-to-batch consistency and traceability. Identity, purity, and enantiomeric excess are verified using advanced analytical techniques including HPLC, GC, and chiral chromatography. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.