Description

5-[4-(4-Fluorophenyl)Piperazin-1-Yl]-5-Oxopentanoic Acid is a high-purity synthetic organic compound with a defined piperazine and fluorophenyl pharmacophore, serving as a critical advanced pharmaceutical intermediate. Its value lies in enabling the synthesis of novel, targeted therapeutic agents, particularly within the central nervous system (CNS) and cardiovascular research domains. This compound is essential for pharmaceutical R&D laboratories, medicinal chemistry programs, and fine chemical manufacturers developing next-generation drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting serotonin and dopamine receptor systems.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for CNS-active compounds.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Biochemical Tool Compound: Employed in pharmacological assays to study receptor binding affinity and functional activity.
• Preclinical Development: Utilized in the production of batches for toxicology studies and early-stage formulation development.

Basic Information

Product Name	5-[4-(4-Fluorophenyl)Piperazin-1-Yl]-5-Oxopentanoic Acid
CAS No.	543717-53-9
Molecular Formula	C15H19FN2O3
Molecular Weight	294.33 g/mol
Synonyms	5-Oxo-5-[4-(4-fluorophenyl)-1-piperazinyl]pentanoic acid; 4-Fluorophenylpiperazine valeric acid derivative; 5-(4-(4-Fluorophenyl)piperazine-1-carbonyl)pentanoic acid; FPPOA; 543717-53-9; 5-[4-(4-Fluorophenyl)-1-piperazinyl]-5-oxopentanoic acid; 1-(4-Fluorophenyl)-4-(5-carboxypentanoyl)piperazine
EINECS	Contact for details

Quality Control

Our 5-[4-(4-Fluorophenyl)Piperazin-1-Yl]-5-Oxopentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under anhydrous conditions if necessary to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.