Description

Vicriviroc Malate is a potent and selective small-molecule antagonist of the CCR5 chemokine receptor. This compound is of significant interest in pharmaceutical research and development, particularly for its potential role in modulating immune responses. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutics for inflammatory and infectious diseases. The product is supplied as a high-purity reference standard to support critical preclinical and analytical work.

Application

• Pharmaceutical Reference Standard: Serves as a primary standard for analytical method development, validation, and quality control (QC) of active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a key tool compound in in vitro studies to investigate CCR5 receptor biology, signal transduction pathways, and immune cell migration.
• Drug Discovery & Development: Employed in high-throughput screening (HTS) campaigns and as a lead compound for the design of new CCR5-targeting agents.
• Preclinical Studies: Utilized in animal models to evaluate the pharmacokinetics, efficacy, and safety profiles of CCR5 antagonist candidates.
• Academic Research: Supports fundamental research in immunology, virology, and oncology where the CCR5 pathway is implicated.

Basic Information

Product Name	Vicriviroc Malate
CAS No.	541503-81-5
Molecular Formula	C₂₉H₄₁F₂N₅O₇
Molecular Weight	609.66 g/mol
Synonyms	Vicriviroc (Malate); SCH 417690; SCH-D; 4,4-Difluoro-N-((1S)-3-(3-exo)-3-(3-methyl-5-(1-methylethyl)-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl)cyclohexanecarboxamide (2S)-2-hydroxybutanedioate; 1:1 Malate salt of Vicriviroc; CCR5 Antagonist SCH-D
EINECS	Contact for details

Quality Control

Our Vicriviroc Malate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, identification by spectroscopic methods (IR, NMR, MS), and control of specified impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the material under inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Assay (HPLC)	97.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.