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C23 Globotriaosylceramide (D18:1/23:0) CAS NO 536745-84-3


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CAS No.:536745-84-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

C23 Globotriaosylceramide (D18:1/23:0) is a defined, high-purity glycosphingolipid (GSL) standard, critical for research and analytical applications. This compound serves as an essential reference material for the study of lipid metabolism, cellular signaling, and biomarker discovery. It is particularly valuable for scientists and quality control laboratories in the pharmaceutical, diagnostic, and life science research sectors requiring precise analytical standards.

Application

  • Biomedical Research Standard: Used as a certified reference material (CRM) for studying Fabry disease and related lysosomal storage disorders.
  • Analytical Chemistry: Serves as a primary standard for the quantitative analysis of globo-series glycosphingolipids via techniques like LC-MS, HPLC, and TLC.
  • Diagnostic Development: Employed in the calibration and validation of diagnostic assays and kits targeting specific lipid biomarkers.
  • Cell Biology Studies: Utilized in research on cell membrane structure, lipid rafts, and glycosphingolipid-mediated cellular processes.
  • Pharmaceutical R&D: Acts as a key substrate or inhibitor in enzyme activity assays and drug discovery screening for therapeutic agents.

Basic Information

Product Name C23 Globotriaosylceramide (D18:1/23:0)
CAS No. 536745-84-3
Molecular Formula C71H131NO13
Molecular Weight 1206.83 g/mol
Synonyms Gb3 (D18:1/23:0); Globotriaosylceramide (d18:1/23:0); CD77; Ceramide Trihexoside (CTH); Gal(α1-4)Gal(β1-4)Glc-Cer (d18:1/23:0); Pk antigen; GL-4; 1-O-[α-D-Galactopyranosyl-(1→4)-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-N-tricosanoylsphingosine
EINECS Contact for details

Quality Control

Every batch of C23 Globotriaosylceramide (D18:1/23:0) is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for research-grade biochemicals. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (HPLC, MS, NMR) are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (MS) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 95%
Solubility Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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