Description

3,4,5-Piperidinetriol,2-Methyl-,(2S,3S,4S,5R)-(9Ci) is a high-purity, stereochemically defined piperidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its precise stereochemistry and polyhydroxylated structure make it an invaluable intermediate for the development of complex, biologically active molecules. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, particularly in areas requiring sophisticated carbohydrate or alkaloid mimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially for neurological and metabolic disorders.
• Glycomimetics & Carbohydrate Chemistry: Used in the synthesis of complex sugar analogs and glycomimetic compounds due to its polyhydroxylated piperidine core.
• Alkaloid Synthesis: Serves as a foundational scaffold for constructing indolizidine, pyrrolizidine, and related alkaloid structures with potential therapeutic activity.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes to study enzyme mechanisms, particularly glycosidases and related enzymes.
• Asymmetric Catalysis Ligand Precursor: Potential use as a precursor for chiral ligands or organocatalysts in stereoselective synthesis.
• Academic & Industrial R&D: A valuable reagent for methodological studies in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	3,4,5-Piperidinetriol,2-Methyl-,(2S,3S,4S,5R)-(9Ci)
CAS No.	528593-83-1
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(2S,3S,4S,5R)-2-Methylpiperidine-3,4,5-triol; 2-Methyl-3,4,5-piperidinetriol (2S,3S,4S,5R)-; (2S,3S,4S,5R)-2-Methyl-3,4,5-trihydroxypiperidine; 3,4,5-Trihydroxy-2-methylpiperidine (stereoisomer); 2-Methyl-3,4,5-trihydroxypiperidine (2S,3S,4S,5R)-; Polyhydroxylated Piperidine Derivative; Chiral Piperidinetriol
EINECS	Contact for details

Quality Control

Our 3,4,5-Piperidinetriol,2-Methyl-,(2S,3S,4S,5R)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including chiral purity verification by HPLC. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.