Description

1-(2,4-Dimethyl-Benzenesulfonyl)-Piperazine is a specialized sulfonamide derivative of piperazine, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the sulfonamide moiety for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Can be incorporated into polymer backbones to impart specific thermal or chemical resistance properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-(2,4-Dimethyl-Benzenesulfonyl)-Piperazine
CAS No.	524711-32-8
Molecular Formula	C12H18N2O2S
Molecular Weight	254.35 g/mol
Synonyms	1-(2,4-Dimethylphenyl)sulfonylpiperazine; Piperazine, 1-[(2,4-dimethylphenyl)sulfonyl]-; 2,4-Dimethylbenzenesulfonylpiperazine; 1-(2,4-Dimethylbenzenesulfonyl)piperazine; 1-(2,4-Xylylsulfonyl)piperazine; 524711-32-8; 1-(2,4-Dimethylphenyl)sulphonylpiperazine
EINECS	Contact for details

Quality Control

Our 1-(2,4-Dimethyl-Benzenesulfonyl)-Piperazine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to cGMP guidelines for advanced pharmaceutical intermediate applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.