Description

Becocalcidiol is a high-purity, synthetic vitamin D3 analog with significant biological activity. This compound is critical for research and development in the pharmaceutical and nutraceutical sectors, where precise molecular structure and purity are paramount. It serves as a key intermediate or active ingredient for scientists and manufacturers developing advanced therapeutic and nutritional formulations targeting calcium homeostasis and bone health.

Application

• Pharmaceutical Research & Development: As a reference standard or active pharmaceutical ingredient (API) in the development of treatments for osteoporosis, renal osteodystrophy, and hypoparathyroidism.
• Nutraceutical Formulations: Used in the production of high-potency dietary supplements and fortified foods aimed at supporting bone density and immune function.
• Biochemical Research: A vital tool for in-vitro and in-vivo studies investigating the vitamin D endocrine system, receptor binding, and gene expression regulation.
• Veterinary Medicine: Incorporated into feed additives or therapeutic products for livestock and companion animals to prevent metabolic bone diseases.
• Cosmeceutical Applications: Investigated for use in topical formulations for skin conditions like psoriasis due to its role in cell differentiation and proliferation.

Basic Information

Product Name	Becocalcidiol
CAS No.	524067-21-8
Molecular Formula	C27H44O3
Molecular Weight	416.64 g/mol
Synonyms	1α,25-Dihydroxy-22-oxavitamin D3; 22-Oxacalcitriol; 1α,25-Dihydroxy-22-oxacholecalciferol; 22-Oxa-1α,25-dihydroxyvitamin D3; OCT; Becocalcidiolum; 22-Oxacalcitriol (Becocalcidiol); 1α,25-Dihydroxy-22-oxa-vitamin D3
EINECS	Contact for details

Quality Control

Our Becocalcidiol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data supporting identity, purity, and potency, compliant with relevant guidelines for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), related substances, and residual solvents is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) at controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.