Description

(4-Phenylpiperazin-1-Yl)[1-(Phenylsulfonyl)Piperidin-3-Yl]Methanone is a high-purity, advanced pharmaceutical intermediate with a complex piperazine-piperidinone sulfonyl scaffold. This compound matters for its critical role as a key building block in the research and development of novel bioactive molecules, particularly in central nervous system (CNS) and receptor-targeted therapies. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to synthesize potential drug candidates for neurological and psychiatric disorders.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• CNS Drug Development: Serves as a core scaffold in the research of potential treatments for conditions like schizophrenia, depression, and anxiety disorders.
• Receptor Ligand Synthesis: Employed in creating selective ligands for serotonin, dopamine, or other G-protein-coupled receptors (GPCRs).
• Chemical Biology Probes: Utilized to develop tool compounds for studying specific enzyme or receptor functions in biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	(4-Phenylpiperazin-1-Yl)[1-(Phenylsulfonyl)Piperidin-3-Yl]Methanone
CAS No.	524060-53-5
Molecular Formula	C22H25N3O3S
Molecular Weight	411.52 g/mol
Synonyms	1-[(Phenylsulfonyl)-3-piperidinyl]-4-phenyl-1-piperazinecarboxaldehyde; 1-(Phenylsulfonyl)-3-[(4-phenyl-1-piperazinyl)carbonyl]piperidine; 3-[(4-Phenylpiperazine-1-carbonyl)]-1-(phenylsulfonyl)piperidine; 1-(Benzenesulfonyl)-3-[(4-phenylpiperazin-1-yl)carbonyl]piperidine; (4-Phenylpiperazin-1-yl)(1-(phenylsulfonyl)piperidin-3-yl)methanone; 524060-53-5; Methanone, (4-phenyl-1-piperazinyl)[1-(phenylsulfonyl)-3-piperidinyl]-
EINECS	Contact for details

Quality Control

Our (4-Phenylpiperazin-1-Yl)[1-(Phenylsulfonyl)Piperidin-3-Yl]Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency for your critical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.