Description

7-Azabicyclo[2.2.1]Heptane-1-Carboxylicacid,2-Oxo-,Methylester,(1S,4R)-(9Ci) is a high-value, stereochemically defined bicyclic lactam derivative. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate, enabling the synthesis of complex molecules with precise three-dimensional architecture. It is essential for research and development in medicinal chemistry, particularly for pharmaceutical companies and CDMOs focused on novel active pharmaceutical ingredients (APIs) in therapeutic areas such as neurology and virology.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Asymmetric Synthesis: Employed as a scaffold or precursor in catalytic asymmetric reactions to introduce stereogenic centers.
• Protease Inhibitor Development: Potential building block for the core structure of inhibitors targeting various enzymes.
• Chemical Biology: Useful for creating molecular probes to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Item	Details
Product Name	7-Azabicyclo[2.2.1]Heptane-1-Carboxylicacid,2-Oxo-,Methylester,(1S,4R)-(9Ci)
CAS No.	523988-22-9
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	(1S,4R)-Methyl 2-oxo-7-azabicyclo[2.2.1]heptane-1-carboxylate; (1S,4R)-1-(Methoxycarbonyl)-7-azabicyclo[2.2.1]heptan-2-one; (1S,4R)-2-Oxo-7-azabicyclo[2.2.1]heptane-1-carboxylic acid methyl ester; 7-Azabicyclo[2.2.1]heptane-1-carboxylic acid, 2-oxo-, methyl ester, (1S,4R)-; (1S,4R)-7-Azabicyclo[2.2.1]heptane-1-carboxylic acid, 2-oxo-, methyl ester; Methyl (1S,4R)-2-oxo-7-azabicyclo[2.2.1]heptane-1-carboxylate
EINECS	Contact for details

Quality Control

Our 7-Azabicyclo[2.2.1]Heptane-1-Carboxylicacid,2-Oxo-,Methylester,(1S,4R)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support development from research to commercial scale with consistent quality and full regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.