Description

1-[(2,3-Dichlorophenyl)Methyl]Piperazine is a high-purity, functionalized piperazine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for constructing complex molecular architectures, particularly in the pharmaceutical sector. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the piperazine moiety's prevalence in bioactive molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the dichlorophenyl group can contribute to biological activity and binding affinity.
• Ligand Synthesis: Acts as a starting material for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific, high-value compounds under cGMP conditions.
• Academic & R&D: Utilized in university and institutional laboratories for methodological studies in organic chemistry and medicinal chemistry programs.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced materials with specific electronic or structural properties.

Basic Information

Product Name	1-[(2,3-Dichlorophenyl)Methyl]Piperazine
CAS No.	523980-04-3
Molecular Formula	C11H14Cl2N2
Molecular Weight	245.15 g/mol
Synonyms	1-[(2,3-Dichlorophenyl)methyl]piperazine; N-[(2,3-Dichlorophenyl)methyl]piperazine; 1-(2,3-Dichlorobenzyl)piperazine; (2,3-Dichlorobenzyl)piperazine; Piperazine, 1-[(2,3-dichlorophenyl)methyl]-; 523980-04-3; 2,3-Dichloro-α-(piperazin-1-ylmethyl)benzene
EINECS	Contact for details

Quality Control

Our 1-[(2,3-Dichlorophenyl)Methyl]Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our standard grade meets high-purity research specifications, and we can support development toward cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.