Description

1-[[4-(Trifluoromethyl)Phenyl](3,4,5-Trimethoxyphenyl)Methyl]Piperazine is a high-value, multifunctional piperazine derivative characterized by its unique trifluoromethyl and trimethoxyphenyl substituents. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of novel chemical entities. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and insecticides with enhanced activity and selectivity.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate for creating specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Serves as a scaffold for developing molecular probes to study biological pathways.
• Custom Synthesis: Foundation for contract research organizations (CROs) and CDMOs to synthesize client-specific target molecules.

Basic Information

Product Name	1-[[4-(Trifluoromethyl)Phenyl](3,4,5-Trimethoxyphenyl)Methyl]Piperazine
CAS No.	518289-30-0
Molecular Formula	C21H25F3N2O3
Molecular Weight	410.43 g/mol
Synonyms	1-[(4-Trifluoromethylphenyl)(3,4,5-trimethoxyphenyl)methyl]piperazine; 1-[[4-(Trifluoromethyl)phenyl](3,4,5-trimethoxyphenyl)methyl]piperazine; 1-((4-(Trifluoromethyl)phenyl)(3,4,5-trimethoxyphenyl)methyl)piperazine; 1-[(3,4,5-Trimethoxyphenyl)(4-trifluoromethylphenyl)methyl]piperazine; Piperazine, 1-[[4-(trifluoromethyl)phenyl](3,4,5-trimethoxyphenyl)methyl]-; 518289-30-0; (4-(Trifluoromethyl)phenyl)(3,4,5-trimethoxyphenyl)(piperazin-1-yl)methane
EINECS	Contact for details

Quality Control

Our production of 1-[[4-(Trifluoromethyl)Phenyl](3,4,5-Trimethoxyphenyl)Methyl]Piperazine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality systems support development from research to commercial scale under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.