Description

1-(1,3-Benzodioxol-5-Yl[4-(Trifluoromethyl)Phenyl]Methyl)Piperazine is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular architecture. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological receptors.
• Drug Discovery & Research: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in API production.
• Biochemical Research: Potential use as a tool compound in pharmacological assays and biochemical studies to investigate specific biological pathways.

Basic Information

Product Name	1-(1,3-Benzodioxol-5-Yl[4-(Trifluoromethyl)Phenyl]Methyl)Piperazine
CAS No.	518004-58-5
Molecular Formula	C20H19F3N2O2
Molecular Weight	376.37 g/mol
Synonyms	1-[(1,3-Benzodioxol-5-yl)[4-(trifluoromethyl)phenyl]methyl]piperazine; 1-(Benzo[d][1,3]dioxol-5-yl(4-(trifluoromethyl)phenyl)methyl)piperazine; Piperazine, 1-[(1,3-benzodioxol-5-yl)[4-(trifluoromethyl)phenyl]methyl]-; 518004-58-5; BDB-TFMP-Piperazine
EINECS	Contact for details

Quality Control

Our 1-(1,3-Benzodioxol-5-Yl[4-(Trifluoromethyl)Phenyl]Methyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.