Description

3-[4-(2-Fluorophenyl)Piperazin-1-Yl]-1-[3-(Trifluoromethyl)Phenyl]Pyrrolidine-2,5-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating piperazine and pyrrolidine-2,5-dione (succinimide) moieties. This compound is of significant commercial interest for its role as a key building block in the research and development of novel therapeutic agents, particularly within the central nervous system (CNS) and psychiatric drug discovery pipelines. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing proprietary bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates targeting neurological and psychiatric disorders.
• Biochemical Research: Used as a reference standard or a tool compound in pharmacological studies to investigate receptor binding affinity and enzyme inhibition.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs in drug discovery.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions for clinical trial material production.
• Academic Research: Utilized in university and institutional labs for exploratory research in organic synthesis and neuropharmacology.

Basic Information

Product Name	3-[4-(2-Fluorophenyl)Piperazin-1-Yl]-1-[3-(Trifluoromethyl)Phenyl]Pyrrolidine-2,5-Dione
CAS No.	511515-40-5
Molecular Formula	C21H19F4N3O2
Molecular Weight	421.39 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]-3-[4-(2-fluorophenyl)-1-piperazinyl]-2,5-pyrrolidinedione; 3-[4-(2-Fluorophenyl)-1-piperazinyl]-1-[3-(trifluoromethyl)phenyl]-2,5-pyrrolidinedione; 511515-40-5; 3-(4-(2-Fluorophenyl)piperazin-1-yl)-1-(3-(trifluoromethyl)phenyl)pyrrolidine-2,5-dione; Succinimide derivative, fluorophenyl piperazinyl trifluoromethylphenyl.
EINECS	Contact for details

Quality Control

Our 3-[4-(2-Fluorophenyl)Piperazin-1-Yl]-1-[3-(Trifluoromethyl)Phenyl]Pyrrolidine-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing results from HPLC, NMR, and MS analyses. Our quality commitment aligns with the standards expected for pharmaceutical development, supporting our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.