Description

tert-Butyl 4-(3-Methoxyphenyl)piperazine-1-carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its piperazine core for bioactivity.
• Chemical Synthesis: Serves as a protected amine reagent for introducing the 4-(3-methoxyphenyl)piperazine moiety into more complex molecules.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Ligand & Catalyst Development: Potential use in creating novel ligands for metal-catalyzed reactions or as a component in catalyst systems.

Basic Information

Product Name	tert-Butyl 4-(3-Methoxyphenyl)piperazine-1-carboxylate
CAS No.	507263-18-5
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	1-Boc-4-(3-methoxyphenyl)piperazine; tert-Butyl 4-(3-methoxyphenyl)-1-piperazinecarboxylate; 4-(3-Methoxyphenyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-methoxyphenyl)piperazine; 3-Methoxyphenylpiperazine-1-Boc; Boc-3-MeO-PPZ; 507263-18-5
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Methoxyphenyl)piperazine-1-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.