Description

Piperazinone, 6-(Phenylmethyl)-, (6S)- (9Ci) is a chiral, non-natural amino acid derivative belonging to the piperazinone class of heterocyclic compounds. This high-purity intermediate is critical for the synthesis of complex, biologically active molecules, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the life sciences sector for constructing novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Peptidomimetic Development: Serves as a constrained scaffold for designing peptide analogs with enhanced metabolic stability and bioavailability.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective chemical transformations.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and protein-protein interactions.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Item	Detail
Product Name	Piperazinone, 6-(Phenylmethyl)-, (6S)- (9Ci)
CAS No.	503186-95-6
Molecular Formula	C11H14N2O
Molecular Weight	190.24 g/mol
Synonyms	(6S)-6-Benzylpiperazin-2-one; (S)-6-Benzylpiperazin-2-one; 6-Benzyl-2-piperazinone, (S)-; L-6-Benzyl-2-piperazinone; (S)-6-Benzyl-2-piperazinone; (S)-6-Benzyl-2-oxopiperazine; (6S)-6-(Phenylmethyl)-2-piperazinone; 2-Piperazinone, 6-(phenylmethyl)-, (6S)-
EINECS	Contact for details

Quality Control

Our Piperazinone, 6-(Phenylmethyl)-, (6S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and chiral integrity. We support development with material suitable for use under cGMP guidelines for non-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.