Description

(S)-2-tert-Butyl-Piperazine is a high-purity, single-enantiomer chiral building block of significant importance in modern synthetic chemistry. Its value lies in its rigid, sterically hindered structure, which is crucial for imparting specific three-dimensional orientation and stability in advanced molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and sophisticated ligands for catalysis.

Application

• As a key chiral intermediate in the synthesis of novel pharmaceutical candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Utilized in the research and development of asymmetric catalysts and chiral ligands for enantioselective synthesis.
• Incorporated into the molecular scaffold of advanced agrochemicals to enhance biological activity and selectivity.
• Serves as a building block for specialty polymers and materials science applications requiring specific stereochemistry.
• Used in academic and industrial research for studying structure-activity relationships (SAR) and molecular recognition.

Basic Information

Item	Details
Product Name	(S)-2-tert-Butyl-Piperazine
CAS No.	502482-37-3
Molecular Formula	C8H18N2
Molecular Weight	142.24 g/mol
Synonyms	(S)-2-tert-Butylpiperazine; (S)-2-(1,1-Dimethylethyl)piperazine; (S)-2-tert-Butyl-piperazine; (S)-2-(tert-Butyl)piperazine; (2S)-2-(1,1-Dimethylethyl)piperazine; (S)-(-)-2-tert-Butylpiperazine; 502482-37-3; (S)-2-t-Butylpiperazine
EINECS	Contact for details

Quality Control

Our (S)-2-tert-Butyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity (assay), enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.