Description

1-Boc-4-[(3,4-Difluorophenyl)Amino]-Piperidine is a high-value, protected piperidine derivative that serves as a critical synthetic intermediate in modern organic chemistry. This compound is essential for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry Development: Serves as a starting material or advanced intermediate in the scale-up and route development for active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Intermediate in the research and production of novel herbicides, fungicides, or insecticides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Institutional Research: Used in universities and research institutes for methodological development and exploratory synthesis.

Basic Information

Product Name	1-Boc-4-[(3,4-Difluorophenyl)Amino]-Piperidine
CAS No.	501674-22-2
Molecular Formula	C16H22F2N2O2
Molecular Weight	312.36 g/mol
Synonyms	1-Boc-4-[(3,4-difluorophenyl)amino]piperidine; tert-Butyl 4-[(3,4-difluorophenyl)amino]piperidine-1-carboxylate; N-(3,4-Difluorophenyl)-1-(tert-butoxycarbonyl)piperidin-4-amine; 1-Boc-4-(3,4-difluoroanilino)piperidine; 4-[(3,4-Difluorophenyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-[(3,4-difluorophenyl)amino]piperidine; Boc-4-(3,4-difluoroanilino)piperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-[(3,4-Difluorophenyl)Amino]-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.