Description

tert-Butyl 3-phenethylpiperazine-1-carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system (CNS).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing diverse compound libraries in drug discovery programs for hit-to-lead optimization.
• Process Chemistry Development: Used in route scouting and scale-up studies for the efficient production of complex drug candidates.
• Building Block for Bioactive Molecules: Facilitates the synthesis of compounds with potential activity in neurological, psychiatric, and other therapeutic areas.
• Agrochemical Research: Employed in the development of novel crop protection agents and pesticides.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals for clients.

Basic Information

Product Name	tert-Butyl 3-phenethylpiperazine-1-carboxylate
CAS No.	500129-54-4
Molecular Formula	C17H26N2O2
Molecular Weight	290.40 g/mol
Synonyms	1-Boc-3-phenethylpiperazine; tert-Butyl 3-(2-phenylethyl)piperazine-1-carboxylate; 3-Phenethylpiperazine-1-carboxylic acid tert-butyl ester; 1-N-Boc-3-phenethylpiperazine; Boc-3-phenethylpiperazine; 500129-54-4; 3-(2-Phenylethyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-phenethylpiperazine-1-carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.