Description

Sulindac Sulfone is a key pharmaceutical intermediate and metabolite of the non-steroidal anti-inflammatory drug (NSAID) Sulindac. Its primary commercial value lies in its critical role in the synthesis and analytical profiling of the parent drug, ensuring quality and consistency in pharmaceutical manufacturing. This compound is essential for research and development laboratories, analytical chemists, and manufacturers in the global pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis and research of Sulindac and related anti-inflammatory compounds.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control testing in pharmaceutical labs.
• Metabolite Studies: Employed in pharmacokinetic and pharmacodynamic research to study the metabolism, efficacy, and safety profile of Sulindac.
• Impurity Profiling: Serves as a known impurity standard to monitor and control the quality of Sulindac active pharmaceutical ingredient (API) batches.
• Biochemical Research: Investigated for its own potential biological activities and mechanisms in various in-vitro and in-vivo studies.

Basic Information

Product Name	Sulindac Sulfone
CAS No.	59973-80-7
Molecular Formula	C20H17FO3S
Molecular Weight	356.41 g/mol
Synonyms	(Z)-5-Fluoro-2-methyl-1-[(4-methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid; FGN-1; Sulindac Sulfoxide; Sulindac Sultone; (Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid; Z-Sulindac sulfone; Aflodac
EINECS	Contact for details

Quality Control

Our Sulindac Sulfone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assay by HPLC, and control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and pharmaceutical-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.