Description

Piperazin-1-Yl-Thiophen-3-Yl-Methanone is a high-value heterocyclic building block featuring a piperazine ring linked to a thiophene carbonyl moiety. This compound matters as a versatile and critical intermediate in modern pharmaceutical research and development, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of central nervous system (CNS) active compounds, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel fungicides, herbicides, and insecticides, leveraging its heterocyclic scaffold.
• Chemical Biology & Proteomics: Serves as a precursor for designing chemical probes and activity-based protein profiling (ABPP) reagents.
• Material Science: Potential building block for organic electronic materials and functional polymers due to the electron-rich thiophene unit.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and library production.

Basic Information

Product Name	Piperazin-1-Yl-Thiophen-3-Yl-Methanone
CAS No.	59939-74-1
Molecular Formula	C9H12N2OS
Molecular Weight	196.27 g/mol
Synonyms	(3-Thienyl)(1-piperazinyl)methanone; 1-(3-Thienylcarbonyl)piperazine; 3-(Piperazine-1-carbonyl)thiophene; 1-Piperazinyl 3-thienyl ketone; 3-Piperazin-1-ylcarbonylthiophene; Thiophene-3-carboxylic acid piperazide; Piperazin-1-yl thiophen-3-yl methanone
EINECS	Contact for details

Quality Control

Our Piperazin-1-Yl-Thiophen-3-Yl-Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for advanced research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.