Description

1-(3-Hydroxyphenyl)Piperazine CAS NO 59817-32-2 is a versatile aromatic piperazine derivative, serving as a crucial pharmaceutical intermediate and research chemical for the synthesis of complex bioactive molecules. Its unique structure, featuring both a phenolic hydroxyl group and a piperazine ring, makes it a valuable building block for medicinal chemistry and drug discovery programs. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used as a scaffold or building block for designing and synthesizing novel drug candidates in academic and industrial R&D.
• Ligand Synthesis: Employed in the preparation of chelating agents or ligands for metal complexes used in catalysis or imaging.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Polymer Modification: Can be used to introduce functional groups into polymer chains to alter material properties.

Basic Information

Item	Details
Product Name	1-(3-Hydroxyphenyl)Piperazine
CAS No.	59817-32-2
Molecular Formula	C10H14N2O
Molecular Weight	178.23 g/mol
Synonyms	3-(1-Piperazinyl)phenol; 3-Hydroxyphenylpiperazine; m-Hydroxyphenylpiperazine; 1-(3-Hydroxyphenyl)piperazine; 1-(m-Hydroxyphenyl)piperazine; 3-Piperazin-1-ylphenol; 59817-32-2
EINECS	Contact for details

Quality Control

Our 1-(3-Hydroxyphenyl)Piperazine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports its use in GMP-aligned pharmaceutical development and other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.