Description

4-(2-Chloro-Acetyl)-Piperazin-2-One is a versatile and high-purity pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of complex molecules, enabling the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for advanced organic synthesis and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds and potential drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Used as a building block for constructing pharmacologically active molecules, including potential kinase inhibitors and other targeted therapies.
• Agrochemical Research: Employed in the development of new pesticides and herbicides, leveraging its reactive chloroacetyl and piperazinone functional groups.
• Fine Chemical Production: Serves as a specialized intermediate for creating custom chemicals and high-value compounds for various industrial applications.
• Chemical Biology Probes: Utilized in research to develop molecular probes for studying biological pathways and enzyme functions.
• Academic & R&D: A valuable reagent for synthetic organic chemistry studies in university and corporate research laboratories.

Basic Information

Product Name	4-(2-Chloro-Acetyl)-Piperazin-2-One
CAS No.	59701-84-7
Molecular Formula	C6H9ClN2O2
Molecular Weight	176.60 g/mol
Synonyms	2-(2-Chloroacetyl)-1,4-diazacyclohexan-5-one; 1-(2-Chloroacetyl)piperazine-2-one; 4-(Chloroacetyl)-2-piperazinone; 2-Piperazinone, 4-(2-chloroacetyl)-; 4-(2-Chloroacetyl)piperazin-2-one; 2-Chloro-1-(2-oxopiperazin-4-yl)ethanone; N-(2-Chloroacetyl)piperazin-2-one
EINECS	Contact for details

Quality Control

Our 4-(2-Chloro-Acetyl)-Piperazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.