Description

Dichloromethylenetris(Dimethylamino)Phosphorane is a highly reactive and versatile organophosphorus reagent, primarily valued for its role as a powerful dehydrating and coupling agent in complex organic synthesis. Its unique structure makes it an essential tool for constructing carbon-nitrogen and carbon-carbon bonds under mild conditions. This compound is particularly critical for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing active ingredients and novel polymers.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the preparation of heterocyclic compounds, peptides, and other bioactive molecules.
• Agrochemical Production: Used in the synthesis of advanced pesticide and herbicide intermediates.
• Polymer Chemistry: Acts as a monomer or catalyst in the production of specialized phosphatzene polymers and flame-retardant materials.
• Peptide Coupling: An effective reagent for forming peptide bonds, serving as an alternative to traditional carbodiimide-based methods.
• Nucleic Acid Chemistry: Employed in the synthesis of nucleotide analogs and modified oligonucleotides.
• Material Science Research: Utilized in the development of novel ligands for catalysis and advanced functional materials.

Basic Information

Product Name	Dichloromethylenetris(Dimethylamino)Phosphorane
CAS No.	59578-17-5
Molecular Formula	C7H18Cl2N3P
Molecular Weight	246.12 g/mol
Synonyms	Tris(dimethylamino)dichloromethylenephosphorane; Dichloromethylene-tris(dimethylamino)phosphorane; Phosphorane, dichloromethylenetris(dimethylamino)-; (Dichloromethylene)tris(dimethylamino)phosphorane; BTPP Chloroform Adduct; Tris(dimethylamino)(dichloromethylene)phosphorane; Chloroform-Tris(dimethylamino)phosphine Complex
EINECS	Contact for details

Quality Control

Our Dichloromethylenetris(Dimethylamino)Phosphorane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot undergoes comprehensive analytical testing, including NMR, HPLC, and titration methods, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (e.g., THF, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.