Description

1-Palmitoyl-2-Docosahexaenoyl-Sn-Glycero-3-Phosphocholine is a high-purity, structured phospholipid, specifically a phosphatidylcholine (PC) species with defined fatty acid chains at the sn-1 and sn-2 positions. This compound is critical for advanced research and formulation due to its role in modeling complex biological membranes and its potential bioactive properties. It is essential for scientists and manufacturers in the pharmaceutical, nutraceutical, and advanced lipidomics sectors who require precise, well-characterized lipid components for drug delivery systems, biomarker research, and high-value nutritional supplements.

Application

• Liposome & Drug Delivery Research: A key component for constructing model membranes and liposomal formulations to study membrane fluidity, permeability, and targeted delivery mechanisms.
• Biochemical & Cell Biology Studies: Used as a standard or substrate in enzymatic assays, signal transduction research, and studies on lipid metabolism and membrane biophysics.
• Nutraceutical & Pharmaceutical Development: Incorporated into high-end formulations for cognitive health and infant nutrition, leveraging the bioactive profile of DHA (docosahexaenoic acid).
• Analytical Reference Standard: Serves as a critical standard in mass spectrometry-based lipidomics for the accurate identification and quantification of complex phospholipid species in biological samples.
• Cosmetic Actives: Used in advanced skincare formulations for its potential membrane-stabilizing and barrier-enhancing properties.

Basic Information

Product Name	1-Palmitoyl-2-Docosahexaenoyl-Sn-Glycero-3-Phosphocholine
CAS No.	59403-54-2
Molecular Formula	C46H82NO8P
Molecular Weight	808.12 g/mol
Synonyms	PC(16:0/22:6); 1-Palmitoyl-2-docosahexaenoyl-phosphatidylcholine; DHA-rich Phosphatidylcholine; PDPC; 1-Hexadecanoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine; (2R)-2,3-Bis[[(Z)-hexadec-9-enoyl]oxy]propyl 2-(trimethylazaniumyl)ethyl phosphate; Phosphatidylcholine (16:0/22:6(n-3))
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Docosahexaenoyl-Sn-Glycero-3-Phosphocholine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical characterization using techniques such as NMR, HPLC, and MS to ensure identity, purity, and fatty acid positional specificity. Certificates of Analysis (COA) detailing all relevant specifications are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). This product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Once opened, purge the container with inert gas and reseal immediately.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95% (Area %)
Fatty Acid Composition (GC)	sn-1: ≥98% Palmitic Acid (C16:0) sn-2: ≥98% Docosahexaenoic Acid (C22:6 n-3)
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.