Description

1-Palmitoyl-2-Stearoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid with a defined fatty acid composition. This compound is a critical component for constructing biomimetic lipid bilayers and serves as a key raw material in advanced pharmaceutical and cosmetic formulations. It is essential for researchers and manufacturers in the liposome, drug delivery, and advanced cosmetic industries who require precise and reproducible lipid components for their products.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A primary building block for creating stable, uniform liposomes used in drug delivery systems for vaccines, mRNA therapies, and targeted cancer treatments.
• Biomembrane Research: Used as a standard phospholipid in model membrane studies (e.g., vesicles, supported lipid bilayers) to investigate membrane fluidity, protein-lipid interactions, and permeability.
• Cosmetic and Dermal Delivery Systems: Incorporated into nanocarriers and creams to enhance the skin penetration and stability of active ingredients like vitamins, antioxidants, and anti-aging compounds.
• Diagnostic Reagent Development: Serves as a substrate or membrane component in diagnostic assays and biosensors.
• Cell Culture and Biotechnology: Used to supplement serum-free media or create defined culture environments for sensitive cell lines.
• Reference Standard: Acts as a high-purity analytical standard for quality control and research in lipidomics and pharmaceutical development.

Basic Information

Product Name	1-Palmitoyl-2-Stearoyl-Sn-Glycero-3-Phosphocholine
CAS No.	59403-51-9
Molecular Formula	C41H82NO8P
Molecular Weight	748.06 g/mol
Synonyms	PSPC; 16:0-18:0 PC; 1-Palmitoyl-2-stearoyl-phosphatidylcholine; Palmitoyl Stearoyl Phosphatidylcholine; (2R)-2,3-Bis(hexadecanoyloxy)propyl (2-(trimethylazaniumyl)ethyl) phosphate; 1-Hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine; L-α-Phosphatidylcholine, 1-palmitoyl-2-stearoyl-; POPC (Note: This is a common but incorrect abbreviation; the correct abbreviation for this specific lipid is PSPC).
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Stearoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, fatty acid profile, and solvent residues is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. For long-term storage, desiccate at -20°C. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Fatty Acid Composition (GC)	Palmitic acid (C16:0): 45-55% Stearic acid (C18:0): 45-55%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.